Galactomannan Testing for Early Diagnosis of Exserohilum rostratum Infection

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Galactomannan testing for early diagnosis of Exserohilum rostratum infection.

Exserohilum rostratum is the most common pathogen in the current U.S. outbreak of fungal central nervous system infection, septic arthritis, and localized spinal or paraspinal infections (1). Rapid laboratory diagnosis is urgently needed but is unfortunately still limited. Only 30% of the 372 case patient specimens sent to the Centers for Disease Control and Prevention (CDC) had PCR evidence su...

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Questionable utility of galactomannan testing for diagnosis of Exserohilum rostratum infection.

With interest, we read the paper by Korem et al. describing a case of Exserohilum rostratum sinusitis from which serum galactomannan (GM) levels were elevated upon diagnosis (1). They further demonstrated that the extract of the E. rostratum clinical isolate yielded positive GM results comparable to those generated by Aspergillus fumigatus. The authors concluded that the GM testing, approved by...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2013

ISSN: 0095-1137

DOI: 10.1128/jcm.00955-13